1. What is a Column Flow Rate Converter?

Definition: This calculator converts linear flow rate (cm/h) to volumetric flow rate (mL/min) for chromatography applications.

Purpose: It helps researchers and lab technicians convert between these common flow rate units used in column chromatography.

2. How Does the Converter Work?

The converter uses the formula:

Where:

• \( Q_{mL/min} \) — Volumetric flow rate (milliliters per minute)
• \( Q_{cm/h} \) — Linear flow rate (centimeters per hour)
• \( 0.01667 \) — Conversion factor (1/60)

Explanation: The conversion factor accounts for both the time unit conversion (hours to minutes) and the volume-to-length relationship in a chromatography column.

3. Importance of Flow Rate Conversion

Details: Proper flow rate conversion ensures accurate method scaling, consistent separation quality, and correct pump settings in chromatography systems.

4. Using the Converter

Tips: Enter the linear flow rate in cm/h. The result will show the equivalent volumetric flow rate in mL/min.

5. Frequently Asked Questions (FAQ)

Q1: Why convert between these units?
A: Linear flow rate (cm/h) is useful for method development while volumetric flow rate (mL/min) is needed for instrument programming.

Q2: Does this conversion depend on column dimensions?
A: The basic conversion doesn't, but the actual volumetric flow rate needed will depend on your column's cross-sectional area.

Q3: What's a typical flow rate range?
A: For HPLC, common linear flow rates range from 50-500 cm/h, corresponding to ~0.8-8.3 mL/min for a 4.6mm ID column.

Q4: Can I use this for different column diameters?
A: This gives the basic conversion. For different diameters, multiply the result by (radius²/standard radius²).

Q5: Is the conversion factor exact?
A: Yes, 0.01667 is exactly 1/60, providing precise conversion between these units.