Flow Rate Formula:
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Definition: This calculator determines the flow rate through a gas chromatography (GC) column based on linear velocity and cross-sectional area.
Purpose: It helps analytical chemists and laboratory technicians optimize GC method parameters and ensure proper column operation.
The calculator uses the formula:
Where:
Explanation: The formula converts linear velocity to volumetric flow rate while accounting for unit conversions.
Details: Proper flow rate ensures optimal separation efficiency, prevents column damage, and maintains consistent retention times in GC analysis.
Tips: Enter the linear velocity (typically 20-50 cm/s for capillary columns) and column cross-sectional area (πr² for round columns). All values must be > 0.
Q1: How do I find the column cross-sectional area?
A: For round columns, calculate using \( A = πr² \) where r is the inner radius in cm.
Q2: What's a typical linear velocity for GC?
A: Common values range from 20-50 cm/s, but optimal velocity depends on column type and analytes.
Q3: Why is the conversion factor 60000?
A: It converts cm³/s to mL/min (1 cm³ = 1 mL, 60 s/min × 1000 mL/L).
Q4: Does this work for both packed and capillary columns?
A: Yes, but ensure you use the correct cross-sectional area for your column type.
Q5: How does temperature affect the calculation?
A: The calculation assumes constant temperature. For precise work, account for temperature effects on gas viscosity.